{"id":99873,"date":"2018-11-05T16:17:53","date_gmt":"2018-11-05T21:17:53","guid":{"rendered":"https:\/\/www.gunsamerica.com\/digest\/?p=99873"},"modified":"2024-08-03T20:55:56","modified_gmt":"2024-08-04T01:55:56","slug":"hunt365-deer-gene-discovery-could-lead-to-treatments-for-human-bone-replacement","status":"publish","type":"post","link":"https:\/\/gunsamerica.com\/digest\/hunt365-deer-gene-discovery-could-lead-to-treatments-for-human-bone-replacement\/","title":{"rendered":"Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement"},"content":{"rendered":"<div id=\"attachment_99874\" style=\"width: 410px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-99874\" title=\"Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement\" class=\"wp-image-99874 size-medium\" src=\"https:\/\/www.gunsamerica.com\/digest\/wp-content\/uploads\/2018\/11\/Fallow_deer_in_field-400x246.jpg\" alt=\"Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement\" width=\"400\" height=\"246\" srcset=\"https:\/\/gunsamerica.com\/digest\/wp-content\/uploads\/2018\/11\/Fallow_deer_in_field-400x246.jpg 400w, https:\/\/gunsamerica.com\/digest\/wp-content\/uploads\/2018\/11\/Fallow_deer_in_field-150x92.jpg 150w, https:\/\/gunsamerica.com\/digest\/wp-content\/uploads\/2018\/11\/Fallow_deer_in_field-768x472.jpg 768w, https:\/\/gunsamerica.com\/digest\/wp-content\/uploads\/2018\/11\/Fallow_deer_in_field.jpg 900w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-99874\" class=\"wp-caption-text\">Bucks were Peter Yang&#8217;s inspiration that led him on a 9-year quest to find two genes that are tied to bone tissue growth. <em>(Photo: <a href=\"https:\/\/en.wikipedia.org\/wiki\/Fallow_deer\" target=\"_blank\" class=\"clickTracking\" campaign=\"hunt365-deer-gene-discovery-could-lead-to-treatments-for-human-bone-replacement\" title=\"Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement\">Wikimedia<\/a>)<\/em><\/p><\/div>\n<p>One Stanford University School of Medicine&#8217;s researcher&#8217;s curiosity may lead to breakthrough treatments for bone injury and diseases. It all started with a trip to the Denali National Park in Alaska.<\/p>\n<p>The researcher, Peter Yang, was fascinated by the fact that deer antlers \u2013 bones with both circulation and nervous systems \u2013 grow more than half an inch per day, fall off annually and regenerate the next year.<\/p>\n<p>&#8220;Deer antlers are bony structures that re-grow at very high rates, making them an attractive model for studying rapid bone regeneration,&#8221; said his team <a href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-018-1027-6\" target=\"_blank\" class=\"clickTracking\" campaign=\"hunt365-deer-gene-discovery-could-lead-to-treatments-for-human-bone-replacement\" title=\"Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement\" target=\"_blank\" rel=\"noopener\">in the published study<\/a>.<\/p>\n<p>&#8220;Deer antler formation shares similar biological mechanisms with human bone growth, but deer antlers grow much faster,&#8221; said Yang to the <a href=\"https:\/\/www.nytimes.com\/2018\/10\/30\/science\/deer-antlers-genes.html\" target=\"_blank\" class=\"clickTracking\" campaign=\"hunt365-deer-gene-discovery-could-lead-to-treatments-for-human-bone-replacement\" title=\"Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement\" target=\"_blank\" rel=\"noopener\">Science Times<\/a>. He hopes this research will lead to treatments that &#8220;reproduce the rapid bone growth of deer antlers in human bone.&#8221;<\/p>\n<p>Antlers can make up over a quarter \u2013 up to 28 percent \u2013 of a deer&#8217;s skeletal weight \u2013 with some deer growing antlers that weigh well over 20 pounds in a couple of months.<\/p>\n<p>Deer antlers and human bones form using the same process, but a deer can grow as much antler in a day as a human can a femur in a whole year in puberty. If we can reproduce even a fraction of that kind of bone growth we could use it to seek treatments for diseases like osteopathy and rapidly treat traumatic skeletal injuries.<\/p>\n<p>Scientists were aware that at least two of the genes Yang studied were involved with human bone tissue growth and formation, but not entirely how. By studying farm-raised dear from a young age, even in-vitro, they found the genes linked with bone growth and antler growth.<\/p>\n<p>Following up in the lab, Yang found that the same genes were active in mice as well.<\/p>\n<h2>See Also: <a href=\"https:\/\/www.gunsamerica.com\/kitten-fights-two-deer-and-wins-caught-on-video\/\" target=\"_blank\" class=\"clickTracking\" campaign=\"hunt365-deer-gene-discovery-could-lead-to-treatments-for-human-bone-replacement\" title=\"Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement\">Kitten Fights Two Deer and Wins, on Video!<\/a><\/h2>\n<p>The genes, uhrf1 and s100a10, influence bone growth and tissue mineralization, respectively. In the lab Yang demonstrated that mice with their uhrf1 suppressed showed slow growth, and that mice with a boosted s100a10 showed very rapid tissue calcification.<\/p>\n<p>By limiting their focus to just two genes, the researchers were able to strongly associate their links with bone tissue growth and formation. As mentioned, other studies had evidence that these genes were involved with tissue formation, just not quite how.<\/p>\n<p>While the promise of treating diseases and mending broken and even lost bones is still far away from this \u2013 regrowing lost limbs even further away \u2013 this is a promising path to treating some of the most painful injuries and illnesses out there.<\/p>\n<h2 style=\"text-align: center\">***<a href=\"https:\/\/gunsamerica.com\/\" campaign=\"BuySellGA_Register\" target=\"_blank\" class=\"clickTracking\">Buy and Sell on GunsAmerica!<\/a>***<\/h2>\n","protected":false},"excerpt":{"rendered":"<p>One Stanford University School of Medicine&#8217;s researcher&#8217;s curiosity may lead to breakthrough treatments for bone injury and diseases. It all started with a trip to the Denali National Park in Alaska.<\/p>\n","protected":false},"author":50,"featured_media":99874,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_specdata_upc":"","_specdata_placement":"","footnotes":""},"categories":[1273,1217,461],"tags":[1207,1276],"featured":[4081],"hunt365":[4089],"class_list":{"0":"post-99873","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-huntnews","8":"category-hunt365","9":"category-max-slowik","10":"tag-deer","11":"tag-huntnews","12":"featured-row3","13":"hunt365-hunting"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement<\/title>\n<meta name=\"description\" content=\"&quot;Deer antlers are bony structures that re-grow at very high rates, making them an attractive model for studying rapid bone regeneration,&quot; said the study.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/gunsamerica.com\/digest\/hunt365-deer-gene-discovery-could-lead-to-treatments-for-human-bone-replacement\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Deer Gene Discovery Could Lead to Treatments for Human Bone Replacement\" \/>\n<meta property=\"og:description\" content=\"One Stanford University School of Medicine&#039;s researcher&#039;s curiosity may lead to breakthrough treatments for bone injury and diseases. It all started with a trip to the Denali National Park in Alaska.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/gunsamerica.com\/digest\/hunt365-deer-gene-discovery-could-lead-to-treatments-for-human-bone-replacement\/\" \/>\n<meta property=\"og:site_name\" content=\"Gun Reviews and News | GunsAmerica.com\/Digest\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/gunsamerica\" \/>\n<meta property=\"article:published_time\" content=\"2018-11-05T21:17:53+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-08-04T01:55:56+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/gunsamerica.com\/digest\/wp-content\/uploads\/2018\/11\/Fallow_deer_in_field.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"900\" \/>\n\t<meta property=\"og:image:height\" content=\"553\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Max Slowik\" \/>\n<meta name=\"twitter:card\" 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