The Colt Grizzly is designed as an outdoor carry gun for a wide variety of self-defense uses. It features a stainless steel construction with a 1-piece, full lug barrel with port cuts for increased recoil control. The sights consist of a red ramp front and adjustable rear notch for high visibility. For additional strength and ruggedness, the cylinder is unfluted.

This model is chambered in .357 Magnum and features a stainless finish and a 4.25-inch barrel. It is equipped with Hogue OverMolded rubber grips and is compatible with all Colt Python and Anaconda-style grips. This pistol is also capable of firing .38 Special ammunition.